October 13, 2020Scandinavian Journal of Rheumatology
Short-term transcutaneous non-invasive vagus nerve stimulation may reduce disease activity and pro-inflammatory cytokines in rheumatoid arthritis: results of a pilot study
Why the study?
Does short-term transcutaneous non-invasive vagus nerve stimulation reduce disease activity and pro-inflammatory cytokines in patients with rheumatoid arthritis?
Population
Patients with rheumatoid arthritis (RA)
Design
Other
Follow-up
Short-term
Authors
Discussion
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Member takes
Implication
Hypothesis-generating for n-VNS in RA; larger RCTs needed before clinical consideration.
Structured PICO
Does short-term transcutaneous non-invasive vagus nerve stimulation reduce disease activity and pro-inflammatory cytokines in patients with rheumatoid arthritis?
P
Population
Patients with rheumatoid arthritis (RA)
I
Intervention
Short-term transcutaneous non-invasive vagus nerve stimulation (n-VNS)
O
Outcome
Disease activity and pro-inflammatory cytokinessurrogate
Short-term transcutaneous non-invasive vagus nerve stimulation shows preliminary anti-inflammatory effects in rheumatoid arthritis.
Limitations
- Pilot study
- Requires larger placebo-controlled trials to confirm findings
Cite This Study
Drewes et al. (2020) studied this question.