Why the study?
Does closure of a very small, hemodynamically insignificant patent ductus arteriosus improve the risk:benefit balance compared with observation?
Population
Individuals with a very small, hemodynamically insignificant patent ductus arteriosus (PDA)
Comparison
Closure (surgical or transcatheter) vs Observation
Design
Review
Authors
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Lacks evidence supporting routine closure of small PDAs to prevent IE; leaves open whether intervention improves risk:benefit over observation.
Does closure of a very small, hemodynamically insignificant patent ductus arteriosus improve the risk:benefit balance compared with observation?
The routine closure of very small, hemodynamically insignificant PDAs to prevent infective endocarditis lacks strong evidence, as the risk of IE is extremely low.
Fortescue et al. (2010) studied this question.
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