Baroreflex Gain Predicts Blood Pressure Recovery During Simulated Ventricular Tachycardia in Humans
Why the study?
Does arterial baroreflex gain predict blood pressure recovery during simulated ventricular tachycardia in patients referred for electrophysiological study?
Population
14 patients referred for electrophysiological study
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
Baroreflex gain may aid VT risk stratification in EP patients; hypothesis-generating and should not yet change practice.
Structured PICO
Does arterial baroreflex gain predict blood pressure recovery during simulated ventricular tachycardia in patients referred for electrophysiological study?
P
Population
14 patients referred for electrophysiological study
I
Intervention
Rapid ventricular pacing (VP) at 150 (n=12) or 120 (n=2) bpm to simulate ventricular tachycardia, and nitroprusside infusion to measure baroreflex gain
O
Outcome
Correlation between arterial baroreflex sympathetic gain and recovery of mean arterial pressure (MAP) during rapid ventricular pacingsurrogate
Arterial baroreflex gain is a significant determinant of hemodynamic stability and blood pressure recovery during simulated ventricular tachycardia.
Cite This Study
Hamdan et al. (1999) studied this question.