Why the study?
Does renal denervation lower ambulatory blood pressure in patients with resistant hypertension?
Does renal denervation lower ambulatory blood pressure in patients with resistant hypertension?
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Baseline nighttime systolic blood pressure and its variability can predict the blood pressure-lowering response to renal denervation in patients with resistant hypertension.
=0.01). In the discriminant analysis, baseline average nighttime systolic BP and standard deviation were significant predictors of the systolic BP response in the denervation group only, allowing adequate responder classification of 70% of the patients. Our results show that denervation lowers ambulatory BP homogeneously over 24 hours in patients with resistant hypertension and suggest that nighttime systolic BP and variability are predictors of the BP response to denervation. CLINICAL TRIAL REGISTRATION: URL: https://www.clinicaltrials.gov. Unique identifier: NCT01570777.
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Gosse et al. (2017) studied this question.
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