Key result
Stented angioplasty linked to ~20% lower repeat revascularisation vs. balloon angioplasty, without reducing death or MI.
Why the study?
Does stented angioplasty reduce death and non-fatal MI compared to balloon angioplasty in patients with chronic stable angina and a single de novo coronary lesion?
Observational (n=3,812)
Yes
Does stented angioplasty reduce death and non-fatal MI compared to balloon angioplasty in patients with chronic stable angina and a single de novo coronary lesion?
Hazard Ratio: 0.8 (95% CI 0.69–0.93)
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Prophylactic mechanical plaque sealing of non-significant coronary lesions (<50% stenosis) does not prevent death or non-fatal MI at 1 year, indicating no clinical benefit for this strategy.
Nestor Mercado (2003) conducted an observational in chronic stable angina and a single de novo lesion in a native coronary vessel (n=3,812). Stented angioplasty vs. Balloon angioplasty was evaluated on need for repeat revascularisation (HR 0.80, 95% CI 0.69-0.93). Stented angioplasty reduced the need for repeat revascularisation compared to balloon angioplasty (HR 0.80; 95% CI 0.69-0.93), but did not prevent death and future non-fatal MIs.
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