February 1, 1995Annual Review of Medicine
Left Ventricular Remodeling After Acute Myocardial Infarction
Why the study?
Do angiotensin-converting enzyme (ACE) inhibitors prevent deterioration in ventricular size and function in survivors of acute myocardial infarction?
Population
Survivors of acute myocardial infarction
Design
Review
Authors
Discussion
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Member takes
Implication
May support ACE inhibitor use post-MI to limit remodeling; leaves open need for confirmatory outcome trials.
Structured PICO
Do angiotensin-converting enzyme (ACE) inhibitors prevent deterioration in ventricular size and function in survivors of acute myocardial infarction?
P
Population
Survivors of acute myocardial infarction
I
Intervention
Angiotensin-converting enzyme (ACE) inhibitors
O
Outcome
Deterioration in ventricular size and function (ventricular enlargement) and clinical outcome
ACE inhibitors are effective in preventing ventricular remodeling and improving clinical outcomes in survivors of acute myocardial infarction.
Cite This Study
Marc A. Pfeffer (1995) studied this question.