Why the study?
Does converting enzyme inhibition improve left ventricular remodelling in an experimental myocardial infarction model?
Population
Experimental myocardial infarction model
Design
Preclinical
Authors
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ACE inhibition may attenuate experimental post-MI remodelling; hypothesis-generating with limited translation to massive infarcts.
Does converting enzyme inhibition improve left ventricular remodelling in an experimental myocardial infarction model?
Converting enzyme inhibition attenuates adverse left ventricular remodelling in experimental myocardial infarction, though its efficacy is limited in massive infarcts (>40% loss).
Michel et al. (1995) studied this question.
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