Key result
In rats, AMI increases overall stress on spared myocardium by ~90%, driven by diastolic stress.
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Rat model shows amplified post-MI stress on spared myocardium; hypothesis-generating and should not change practice.
Capasso et al. (1992) studied Acute myocardial infarction. Coronary artery occlusion was evaluated on Extent and distribution of systolic and diastolic wall stress on the surviving myocardium. In rats, acute myocardial infarction induced by coronary occlusion provoked a 1.9-fold increase in overall stress on spared myocardium, with diastolic stress augmented by 6.8-fold.
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