Juçara Berry ( Euterpe edulis Martius ) As a Natural Source of Antioxidants: Modulation of Biochemical and Oxidative Stress Markers in Rats

Juçara (Euterpe edulis), an aça species from the Atlantic Forest, contains a variety of phytochemicals with antioxidant activity, which may be associated with potential health-promoting effects. This study investigated the effects of juçara pulp on biochemical, oxidative stress, and bone and body parameters in rats. Forty male Wistar rats were treated for 30 days and allocated into four groups: control and juçara 50, 100, and 200 mg/kg/day. The pulp exhibited high in vitro antioxidant activity due to its high phenolic content. In vivo, supplementation enhanced systemic antioxidant defense, increasing catalase, superoxide dismutase, and thiols, while reducing protein carbonyl, FOX, and hepatic TBARS, especially at 100–200 mg/kg. Biochemical analysis indicated lowered glycemia, ALT, AST, urea, creatinine, and uric acid, suggesting hepatoprotective and nephroprotective potential. Bone radiodensity was also higher at 100 mg/kg. No adverse effects on growth, body composition, or cytokines were observed, supporting juçara’s potential as a functional food ingredient or nutraceutical.