What question did this study set out to answer?

To determine the incidence of acute respiratory distress syndrome (ARDS) and its clinical and laboratory predictors in septic patients.

May 9, 2026CureusOpen Access

Incidence and Predictors of Acute Respiratory Distress Syndrome in Patients With Sepsis: A Two-Year Prospective Cohort Study From Khyber Pakhtunkhwa, Pakistan

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Prospective cohort study finds high ARDS incidence in sepsis patients, highlighting key predictors.

To determine the incidence of acute respiratory distress syndrome (ARDS) and its clinical and laboratory predictors in septic patients.
Conducted a prospective observational cohort study from March 2023 to February 2025.
Observed adult patients diagnosed with sepsis daily for onset of ARDS according to the Berlin definition.
Performed univariate and multivariable logistic regression analyses to identify independent predictors of ARDS.
Out of 364 septic patients, 108 (29.67%) developed ARDS.
Independent predictors included PaO2/FiO2 <200 mmHg, serum lactate >2 mmol/L, GCS <14, pulmonary infection, SOFA score ≥6, and age ≥60 years.

Khan et al. (2026) studied this question.

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