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The aim is to characterize chromium-doped hydroxyapatite coatings and assess their biological and antibacterial properties.

May 9, 2026BiomimeticsOpen Access

Physico-Chemical and Biological Evaluation of Spin-Coated Chromium-Doped Hydroxyapatite in Dextran Matrix Coatings

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Randomized trial evaluates antibacterial properties of new coatings in vitro, indicating potential for biomedical applications.

The aim is to characterize chromium-doped hydroxyapatite coatings and assess their biological and antibacterial properties.
Coatings were prepared via spin coating technique and characterized using X-ray diffraction and FTIR spectroscopy.
In vitro biocompatibility evaluated using MG63 human osteoblast-like cell line and MTT assay.
Antibacterial effectiveness tested against Pseudomonas aeruginosa and Staphylococcus aureus.
Achieved log reductions of ~9.35 for S. aureus indicating a bacterial kill rate exceeding 99.99%.
10CrHAp-Dx showed slightly superior antibacterial performance compared to 10CrHAp.
Both coatings exhibited sustained antibacterial effects with log reductions of 8.6 and 8.9 against Pseudomonas aeruginosa.

Iconaru et al. (2026) studied this question.

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