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September 10, 2025

The Effect of Surface Roughness and Hydroxyapatite Coating on the Biocompatibility of Co-Cr Alloys for Medical Implants

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Authors

ICIon CiucăBVBogdan Ștefan VasileRTRoxana Truşcă

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Overview

This study demonstrates surface roughness improves biocompatibility and antimicrobial properties of Co-Cr alloys, indicating their potential in medical implants.

Key Points

  • HA-coated Co-Cr alloys with higher surface roughness significantly inhibit Pseudomonas aeruginosa biofilm formation, enhancing antimicrobial performance.
  • The samples showed sustained stability in Simulated Body Fluid, supporting their potential for long-term application in implants.
  • Roughened surfaces (110 µm and 250 µm) displayed improved adhesion and stability in structural assessments using SEM and XRD.
  • Surface roughness positively impacts the effectiveness of HA coatings, crucial for enhancing biocompatibility in medical implants.

Cite This Study

Ciucă et al. (2025) studied this question.

synapsesocial.com/papers/68c1c31254b1d3bfb60f041fhttps://doi.org/10.21203/rs.3.rs-7315375/v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Multi-objective optimization of tribocorrosion parameters and biocompatibility of selective laser melted CoCr alloy2026
  2. 2Physico-Chemical and Biological Evaluation of Spin-Coated Chromium-Doped Hydroxyapatite in Dextran Matrix Coatings2026
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  5. 5Engineered surfaces for biomedical implants: advances in coatings, materials, and techniques2026 · 6 citations