Why the study?
While endothelial dysfunction is closely related to cardiac dysfunction and heart failure in diabetic cardiomyopathy, clinical strategies for restoring endothelial function are still missing.
Design
Review
Authors
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Endothelial dysfunction may link diabetes to heart failure; leaves open whether targeting it improves outcomes in trials.
This review highlights the critical role of endothelial dysfunction in the pathogenesis of diabetic cardiomyopathy and identifies it as a potential therapeutic target.
Wang et al. (2022) studied this question.