Why the study?
Does MRI phase contrast accurately measure stroke volume and flow in turbulent stenotic jets associated with aortic stenosis?
Population
31 patients with moderate to severe aortic stenosis (AS) and in vitro pipe models
Comparison
MRI phase contrast velocity and flow measurement vs Ventricular stroke volume and known flow
Design
Cross-sectional
Authors
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Phase-contrast MRI substantially underestimates stroke volume in aortic stenosis; leaves open whether shorter-TE sequences can improve accuracy in clinical use.
Does MRI phase contrast accurately measure stroke volume and flow in turbulent stenotic jets associated with aortic stenosis?
Current clinically available MRI phase contrast pulse sequences with TE >2 msec may not accurately quantify flow for severe stenotic lesions due to signal loss.
O’Brien et al. (2008) studied this question.
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