November 19, 2018Proceedings of the National Academy of SciencesOpen Access

Biological sex affects vaccine efficacy and protection against influenza in mice

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AFAshley L. FinkCollege of Saint Benedict and Saint John's University KEKyrra EngleInternational Breast Cancer Study Group RURebecca L. UrsinRagon Institute of MGH, MIT and Harvard

Abstract

reduced sex differences in vaccine-induced antibody responses and protection following challenge and had a greater impact on responses in females than males. Taken together, these data illustrate that greater TLR7 activation and antibody production in females improves the efficacy of vaccination against influenza.

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Fink et al. (2018) studied this question.

synapsesocial.com/papers/69ff7a114716aad0cc855b98 https://doi.org/10.1073/pnas.1805268115

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Biological sex affects vaccine efficacy and protection against influenza in mice

Abstract

Discussion

Member takes

Cite This Study

Biological sex affects vaccine efficacy and protection against influenza in mice

Abstract

Discussion

Member takes

Cite This Study

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