Why the study?
Does severe mental illness increase the risk of mortality from coronary heart disease, stroke, and cancer compared to people without severe mental illness?
Population
346,562 individuals from the United Kingdom's General Practice Research Database, comprising 46,136 people…
Comparison
Severe mental illness (SMI) diagnosis (exposure) vs People without severe mental illness diagnoses
Design
Cohort
Authors
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Supports closer CHD surveillance in SMI; leaves open whether interventions reduce excess mortality.
Does severe mental illness increase the risk of mortality from coronary heart disease, stroke, and cancer compared to people without severe mental illness?
Severe mental illness is associated with a significantly increased risk of mortality from coronary heart disease and stroke, which is not fully explained by antipsychotic use, smoking, or social deprivation.
Osborn et al. (2007) studied this question.
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