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May 10, 2026Journal of Medical VirologyOpen Access

Hepatitis C Virus and Type 2 Diabetes: Mechanisms, Clinical Impact, and Post‐DAA Management

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Authors

SCShen‐Shong ChangNational Yang Ming Chiao Tung UniversityCLChing‐Hsuan LiuTaipei Medical UniversitySCShu‐Yen ChanVanderbilt University Medical Center

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Implication

Review discusses mechanisms linking HCV to diabetes complications and strategies for management.

Key Points

  • This review explores the relationships between hepatitis C virus infection and type 2 diabetes, highlighting treatment implications.
  • Comprehensive review of epidemiological and mechanistic studies concerning HCV and type 2 diabetes.
  • Focus on pathways inducing insulin resistance and effects of direct-acting antivirals on diabetes outcomes.
  • HCV infection significantly increases the prevalence of type 2 diabetes and worsens its outcomes.
  • DAA therapies improve insulin resistance and reduce incidence of diabetes and cardiovascular risks.

Cite This Study

Chang et al. (2026) studied this question.

synapsesocial.com/papers/6a0020cec8f74e3340f9ba8chttps://doi.org/10.1002/jmv.70952
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