What question did this study set out to answer?

This research aims to determine how sleep duration moderates the relationship between depressive symptoms and oral microbiome diversity.

May 10, 2026SLEEP

1111 Sleep Duration Moderates the Association Between the Oral Microbiome and Depressive Symptoms Among Emerging Adults in the United States

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Authors

MNMarie‐Rachelle NarcisseBrown University DBDavid BarkerBrown University TCTsute ChenForsyth Technical Community College

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Implication

Randomized trial examines the impact of sleep duration on oral microbiome diversity and depressive symptoms in emerging adults, suggesting critical health connections.

Key Points

This research aims to determine how sleep duration moderates the relationship between depressive symptoms and oral microbiome diversity.
Analyzed data from 1,168 emerging adults (ages 18-26) from the National Health and Nutrition Examination Survey (2011-2012).
Evaluated associations using Generalized Linear Models considering PHQ-9 depression scores and sleep duration categories.
Assessed oral microbiome diversity via specific indices like Shannon-Wiener diversity and operational taxonomic units.
Short sleep durations linked to lower oral microbiome richness and evenness with higher depressive symptom scores (SWD: F3,15=11.77, p<0.001).
Significant interactions observed for oral microbiome metrics with PHQ-9 scores across sleep duration categories (OTU: F3,15=4.94, p=0.027).
Adequate sleep appeared to buffer the negative effects of depressive symptoms on microbial diversity; sleep disorders did not moderate these associations.

Cite This Study

Narcisse et al. (2026) studied this question.

synapsesocial.com/papers/6a002162c8f74e3340f9c3be https://doi.org/10.1093/sleep/zsag091.1110

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Implication

Randomized trial examines the impact of sleep duration on oral microbiome diversity and depressive symptoms in emerging adults, suggesting critical health connections.

1111 Sleep Duration Moderates the Association Between the Oral Microbiome and Depressive Symptoms Among Emerging Adults in the United States

Discussion

Member takes

Implication

Key Points

Cite This Study

1111 Sleep Duration Moderates the Association Between the Oral Microbiome and Depressive Symptoms Among Emerging Adults in the United States

Discussion

Member takes

Implication

Key Points

Cite This Study

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