What question did this study set out to answer?

To determine the incidence and potential clinical risk factors for corticosteroid-unrelated idiopathic central serous chorioretinopathy in an Asian population.

June 24, 2013PLoS ONEOpen Access

Epidemiology of Idiopathic Central Serous Chorioretinopathy in Taiwan, 2001–2006: A Population-based Study

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Authors

DTDer‐Chong Tsai SCShih Jen Chen CHChin-Chou Huang

Discussion

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Overview

Population-based matched case-control study reveals higher rates of central serous chorioretinopathy in middle-aged males, indicating an independent link to anti-anxiety medication.

Key Points

To determine the incidence and potential clinical risk factors for corticosteroid-unrelated idiopathic central serous chorioretinopathy in an Asian population.
Conducted a population-based matched case-control study using Taiwan's National Health Insurance Research Database between 2001 and 2006.
Identified 786 incident cases aged 20–64 years with newly diagnosed idiopathic central serous chorioretinopathy and no history of corticosteroid use (500 males, 63.6%), matched to 3,606 controls by age, sex, and enrollment time.
Assessed independent risk factors using conditional logistic regression to calculate odds ratios.
Mean annual incidence of idiopathic central serous chorioretinopathy was 0.21‰ overall (0.27‰ in males vs. 0.15‰ in females, P < 0.001), with a peak incidence among individuals aged 35–39 years (0.30‰).
Exposure to anti-anxiety drugs was independently associated with the disease among males (OR, 1.63; 95% CI, 1.09–2.44), whereas no independent risk factors were detected among females.

Cite This Study

Tsai et al. (2013) studied this question.

synapsesocial.com/papers/6a004bd810d6befb2577655a https://doi.org/10.1371/journal.pone.0066858

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June 24, 2013PLoS ONEOpen Access

Epidemiology of Idiopathic Central Serous Chorioretinopathy in Taiwan, 2001–2006: A Population-based Study

View Full Paper

Ask AI

Bookmark

Authors

DTDer‐Chong Tsai SCShih Jen Chen CHChin-Chou Huang

Discussion

Member takes

Overview

Population-based matched case-control study reveals higher rates of central serous chorioretinopathy in middle-aged males, indicating an independent link to anti-anxiety medication.

Key Points

To determine the incidence and potential clinical risk factors for corticosteroid-unrelated idiopathic central serous chorioretinopathy in an Asian population.
Conducted a population-based matched case-control study using Taiwan's National Health Insurance Research Database between 2001 and 2006.
Identified 786 incident cases aged 20–64 years with newly diagnosed idiopathic central serous chorioretinopathy and no history of corticosteroid use (500 males, 63.6%), matched to 3,606 controls by age, sex, and enrollment time.
Assessed independent risk factors using conditional logistic regression to calculate odds ratios.
Mean annual incidence of idiopathic central serous chorioretinopathy was 0.21‰ overall (0.27‰ in males vs. 0.15‰ in females, P < 0.001), with a peak incidence among individuals aged 35–39 years (0.30‰).
Exposure to anti-anxiety drugs was independently associated with the disease among males (OR, 1.63; 95% CI, 1.09–2.44), whereas no independent risk factors were detected among females.

Cite This Study

Tsai et al. (2013) studied this question.

synapsesocial.com/papers/6a004bd810d6befb2577655a https://doi.org/10.1371/journal.pone.0066858

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