Why the study?
Many patients with hyperglycemic crises present with combined features of DKA and HHS, but the implications of concomitant acidosis and hyperosmolality are not well known.
Does combined DKA-HHS increase hospital mortality compared to isolated DKA or HHS in patients with hyperglycemic crises?
Does combined DKA-HHS increase hospital mortality compared to isolated DKA or HHS in patients with hyperglycemic crises?
Combined DKA-HHS is associated with higher mortality compared with isolated DKA or HHS, highlighting the need for careful management to avoid severe hypokalemia and hypoglycemia.
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May warrant closer monitoring in combined DKA-HHS; leaves open whether targeted protocols improve survival.
Pasquel et al. (2019) studied this question.
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