Why the study?
Does cycling exercise training improve platelet mitochondrial bioenergetics and functional capacity in patients with peripheral arterial disease?
Does cycling exercise training improve platelet mitochondrial bioenergetics and functional capacity in patients with peripheral arterial disease?
Cycling exercise training improves platelet mitochondrial bioenergetics, functional capacity, and quality of life in patients with peripheral arterial disease.
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Supports cycling exercise in PAD to boost mitochondrial function, capacity, and HRQoL; extends mechanistic evidence beyond standard outcomes.
levels were positively associated with changes in platelet OXPHOS and ETS capacities. However, no significant changes in systemic aerobic capacity, platelet mitochondrial bioenergetics, and health-related quality of life (HRQoL) occurred following GR alone. Hence, we conclude that CET effectively increases the capacities of platelet mitochondrial bioenergetics by enhancing complex II activity in patients with PAD. Moreover, the exercise regimen also enhanced functional exercise capacity, consequently improving HRQoL in PAD patients.
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Fu et al. (2021) studied this question.
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