"Diastolic heart failure" or heart failure caused by subtle left ventricular systolic dysfunction?
Why the study?
Does measurement of left ventricular systolic atrioventricular plane displacement detect subtle systolic dysfunction in patients with suspected heart failure and preserved systolic function by conventional measures?
Population
147 patients with suspected heart failure referred by general practitioners
Comparison
Echocardiographic measurement of left… vs Conventional echocardiographic measures of left…
Design
Cross-sectional
Authors
Discussion
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Implication
May identify subtle systolic dysfunction missed by conventional EF in suspected HFpEF; hypothesis-generating and requires prospective validation.
Key Points
- To assess if patients suspected of heart failure with preserved systolic function have subtle left ventricular systolic dysfunction detectable by new echocardiographic measures.
- Observational study involving 147 patients suspected of heart failure referred by general practitioners.
- Echocardiographic assessment of conventional and new measures of left ventricular systolic function.
- Measurement of left ventricular systolic atrioventricular plane displacement.
- 21% to 33% of patients with 'normal' left ventricular systolic function had abnormal atrioventricular plane displacement.
- Findings indicate these patients may have subtle systolic dysfunction.
Structured PICO
Does measurement of left ventricular systolic atrioventricular plane displacement detect subtle systolic dysfunction in patients with suspected heart failure and preserved systolic function by conventional measures?
P
Population
147 patients with suspected heart failure referred by general practitioners
I
Intervention
Echocardiographic measurement of left ventricular systolic atrioventricular plane displacement
C
Comparator
Conventional echocardiographic measures of left ventricular systolic function (fractional shortening, ejection fraction by Simpson's biplane method, and eyeball assessment)
O
Outcome
Detection of abnormal left ventricular systolic atrioventricular plane displacement in patients with normal conventional systolic functionsurrogate
A significant proportion of patients diagnosed with 'diastolic heart failure' based on normal conventional ejection fraction actually have subtle systolic dysfunction detectable by atrioventricular plane displacement.
Cite This Study
Mark C. Petrie (2002) studied this question.