Registry of Transcatheter Aortic-Valve Implantation in High-Risk Patients
Population
3,195 high-risk elderly patients with severe aortic stenosis and coexisting illnesses, highly symptomatic…
Design
Cohort
Follow-up
1 year
Authors
Discussion
Loading...
Member takes
Implication
Supports TAVI feasibility in high-risk patients; extends real-world data but leaves open comparative effectiveness trials.
Structured PICO
P
Population
3,195 high-risk elderly patients with severe aortic stenosis and coexisting illnesses, highly symptomatic and at high surgical risk for aortic-valve replacement. Mean age 82.7 years, 49% women. French national registry.
I
Intervention
Transcatheter aortic-valve implantation (TAVI) using Edwards SAPIEN (66.9%) or Medtronic CoreValve (33.1%) devices via transarterial or transapical approaches.
O
Outcome
Death from any causehard clinical
In a real-world national registry, TAVI demonstrated a high procedural success rate of 96.9% and a 1-year mortality rate of 24.0% in high-risk elderly patients with severe aortic stenosis.
Cite This Study
Gilard et al. (2012) studied this question.