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January 1, 2016Advances in Interventional CardiologyOpen Access

Early- and mid-term outcomes after transcatheter aortic valve implantation. Data from a single-center registry

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Key result

Transcatheter aortic valve implantation in high-risk elderly patients with severe symptomatic aortic stenosis resulted in a 12-month all-cause mortality rate of 17.8%.

Population

101 consecutive high-risk elderly patients with severe symptomatic aortic stenosis, median age 81.0, 60.4%…

Design

Cohort

Follow-up

12 months

Authors

MBMaciej BagieńskiKrakow Cardiovascular Research InstitutePKPaweł KleczyńskiInterventional CardiologyArtur DziewierzArtur DziewierzInterventional / Structural Cardiology

Discussion

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Implication

May support consideration in selected high-risk elderly patients; leaves open need for randomized confirmation of benefit.

Study Design

Type

Observational (n=101)

Multicenter

No

Structured PICO

P
Population
101 consecutive high-risk elderly patients with severe symptomatic aortic stenosis undergoing transcatheter aortic valve implantation, followed for up to 12 months.
I
Intervention
Transcatheter aortic valve implantation (TAVI) using Edwards Sapien, Edwards Sapien XT, Edwards Sapien 3, Medtronic CoreValve, or JenaValve via transfemoral, transapical, or direct aortic access.
O
Outcome
All-cause mortality at discharge, 30 days, 6 months, and 12 monthshard clinical

TAVI is an effective treatment option for elderly, high-risk patients with severe symptomatic aortic stenosis, demonstrating an acceptable 12-month mortality rate of 17.8% and significant symptom alleviation.

Limitations

  • Relatively small sample size due to limited reimbursement in Poland
  • Results are influenced by the operators' learning curve for TAVI procedures
  • Cannot exclude underreporting of events despite 98% completeness of follow-up
  • relatively small sample size
  • results are influenced by operators' learning curve for TAVI procedures
  • cannot exclude underreporting of events due to 98% completeness of follow-up

Cite This Study

Bagieński et al. (2016) conducted an observational in Severe symptomatic aortic stenosis (n=101). Transcatheter aortic valve implantation (TAVI) was evaluated on All-cause mortality at 12 months. Transcatheter aortic valve implantation in high-risk elderly patients with severe symptomatic aortic stenosis resulted in a 12-month all-cause mortality rate of 17.8%.

synapsesocial.com/papers/6a9590157007bd2ef4e3cc8chttps://doi.org/10.5114/aic.2016.59362
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Transcatheter Versus Surgical Aortic-Valve Replacement in High-Risk Patients2012 · 642 citations
  2. 2The German Aortic Valve Registry (GARY): in-hospital outcome2013 · 337 citations
  3. 3Procedural, 30-day and one year outcome following CoreValve or Edwards transcatheter aortic valve implantation: results of the Belgian national registry2011 · 223 citations
  4. 4Impact of postoperative acute kidney injury on clinical outcomes after transcatheter aortic valve implantation: A meta‐analysis of 5,971 patients2015 · 92 citations
  5. 5Chronic pacing and adverse outcomes after transcatheter aortic valve implantation2015 · 133 citations