May 10, 2012Circulation Cardiovascular ImagingOpen Access

Prediction of Arrhythmic Events in Ischemic and Dilated Cardiomyopathy Patients Referred for Implantable Cardiac Defibrillator

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Why the study?

Does scar signal quantification by LGE-CMR predict arrhythmic events in patients with ICM and DCM referred for ICD therapy?

Population

124 consecutive patients referred for ICD therapy

Design

Cohort, Blinded scar signal quantification

Follow-up

mean 632 ± 262 days

Authors

PGPeng GaoChinese Academy of Medical Sciences & Peking Union Medical College RYRaymond YeeElectrophysiology LGLorne J. GulaElectrophysiology

Discussion

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Implication

May aid arrhythmic risk stratification in ICD referrals; leaves open whether it improves selection in prospective trials.

Structured PICO

Does scar signal quantification by LGE-CMR predict arrhythmic events in patients with ICM and DCM referred for ICD therapy?

Population

124 consecutive patients referred for ICD therapy (59 with ischemic cardiomyopathy [ICM] and 65 with nonischemic dilated cardiomyopathy [DCM])

Intervention

Scar signal quantification using late gadolinium enhancement cardiac magnetic resonance (LGE-CMR)

Outcome

Combined outcome of appropriate ICD therapy, survived cardiac arrest, or sudden cardiac deathcomposite

Myocardial scar quantification by LGE-CMR is a strong independent predictor of arrhythmic events in patients referred for ICD therapy, regardless of cardiomyopathy etiology.

Cite This Study

Gao et al. (2012) studied this question.

synapsesocial.com/papers/6a015967ef8139f8ff77cd90 https://doi.org/10.1161/circimaging.111.971549

Topics

Cardiac device therapy Echocardiography Cardiac MRI Women and heart disease

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Prediction of Arrhythmic Events in Ischemic and Dilated Cardiomyopathy Patients Referred for Implantable Cardiac Defibrillator

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Prediction of Arrhythmic Events in Ischemic and Dilated Cardiomyopathy Patients Referred for Implantable Cardiac Defibrillator

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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