“Maternal Severity from Survival to Death: Gamma Regression Analysis of WHO Organ Dysfunction Markers in South India”

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Key Points

The study aims to examine the relationship between organ dysfunction markers and maternal mortality, enhancing understanding of severe obstetric complications.
Conducted a cross-sectional study from February 2024 to January 2025 at a South Indian tertiary hospital.
Included pregnant and postpartum women meeting WHO near-miss criteria or who experienced maternal death.
Used gamma regression analysis to model associations between severity markers and maternal outcomes.
Out of 4,068 deliveries, 206 had severe outcomes, with 191 near misses and 15 maternal deaths.
Highest mortality linked to interventions, with CPR at 82.4% (RR 154.8), intubation/ventilation at 45.5% (RR 289.4), and severe hypoxemia at 50.0% (RR 11.8).
Gamma regression identified multiorgan dysfunction as the strongest predictor of maternal severity.

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Cross-sectional study examines organ dysfunction severity markers and maternal deaths, indicating improved care quality implications.

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Ramu et al. (2026) studied this question.

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