Why the study?
Does closure with a percutaneous device reduce the composite of stroke, TIA, or death in patients aged 18-60 with cryptogenic stroke or TIA and a patent foramen ovale compared to medical therapy alone?
Does closure with a percutaneous device reduce the composite of stroke, TIA, or death in patients aged 18-60 with cryptogenic stroke or TIA and a patent foramen ovale compared to medical therapy alone?
Percutaneous closure of patent foramen ovale did not offer a greater benefit than medical therapy alone for preventing recurrent stroke or TIA in patients with cryptogenic stroke.
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PFO closure does not reduce recurrent events over medical therapy; confirms medical therapy as standard for cryptogenic stroke with PFO.
Furlan et al. (2012) studied this question.
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