Why the study?
Does medium to large PFO size correlate with embolic brain imaging findings in patients with ischemic stroke?
Population
95 patients with first ischemic stroke over age 39 who underwent transesophageal echocardiography for…
Comparison
Medium to large PFO (≥2 mm) vs Small (<2 mm) or no PFO
Design
Cross-sectional, Stroke subtype and MRI/CT imaging data were evaluated blind…
Authors
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Supports paradoxical embolization in larger PFO stroke cases; hypothesis-generating and should not yet change practice.
Does medium to large PFO size correlate with embolic brain imaging findings in patients with ischemic stroke?
Larger PFOs are associated with a higher frequency of embolic brain imaging features, supporting paradoxical embolization as a stroke mechanism in cryptogenic cases.
Steiner et al. (1998) studied this question.
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