Key result
In patients with acute pulmonary embolism, the presence of a patent foramen ovale was significantly associated with asymptomatic acute and subacute ischaemic lesions on brain MRI (12.8% vs 1.2%, p=0.01).
Population
129 patients with a diagnosis of pulmonary embolism confirmed by CTA
Design
Cross-sectional observational study
Authors
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Should not yet change PE management; hypothesis-generating for PFO screening or closure trials.
Observational (n=129)
No
Absolute Event Rate: 12.8% vs 1.2%
p-value: p=0.01
There is a surprisingly high frequency of asymptomatic acute and subacute ischaemic brain lesions in patients with acute pulmonary embolism, particularly those with a patent foramen ovale.
Nykl et al. (2023) conducted an observational in Acute pulmonary embolism (n=129). Patent foramen ovale vs. No patent foramen ovale was evaluated on Acute and subacute ischaemic lesions on brain MRI (p=0.01). In patients with acute pulmonary embolism, the presence of a patent foramen ovale was significantly associated with asymptomatic acute and subacute ischaemic lesions on brain MRI (12.8% vs 1.2%, p=0.01).
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