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June 18, 2020Health and Quality of Life OutcomesOpen Access

Comparisons of quality of life between patients underwent peritoneal dialysis and hemodialysis: a systematic review and meta-analysis

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Authors

ACAnan ChuasuwanSPSiriporn PooripussarakulATAmmarin Thakkinstian

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Overview

Systematic review and meta-analysis shows better health-related quality of life in peritoneal dialysis versus hemodialysis for kidney disease, indicating distinct mental and symptom benefits.

Key Points

  • To compare health-related quality of life outcomes between end-stage renal disease patients undergoing peritoneal dialysis versus hemodialysis across generic and disease-specific assessment tools.
  • Systematic search of MEDLINE and SCOPUS databases through April 2017 identified 21 eligible studies encompassing 29,000 participants (mean age 48.1 years, 45.1% male).
  • Calculated and pooled unstandardized mean differences (USMD) of HRQoL scores using fixed-effect or random-effects models depending on statistical heterogeneity.
  • SF-36 scores favored peritoneal dialysis over hemodialysis for the mental component summary (USMD 1.86, 95% CI: 0.47 to 3.24), while physical component differences were not statistically significant (USMD 0.42, 95% CI: -1.99 to 2.82).
  • EQ-5D visual analogue scale scores significantly favored peritoneal dialysis (USMD 3.56, 95% CI: 1.73 to 5.39), though utility scores did not differ significantly (USMD 0.02, 95% CI: -0.06 to 0.10).
  • KDQOL instrument scores demonstrated significant advantages for peritoneal dialysis in disease burden (USMD 9.67, 95% CI: 5.67 to 13.68) and symptom distress (USMD 2.10, 95% CI: 0.07 to 4.13).

Cite This Study

Chuasuwan et al. (2020) studied this question.

synapsesocial.com/papers/6a018cb9e8ec6bd19dcaeb37https://doi.org/10.1186/s12955-020-01449-2
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Comparison of Quality of Life in Patients Undergoing Hemodialysis and Peritoneal Dialysis: a Systematic Review and Meta-Analysis2017 · 240 citations
  2. 2#2155 Evaluating the health-related quality of life of patients undergoing haemodialysis: highlights from a multicentric nationwide study2024
  3. 3Comparison of the quality of life in peritoneal dialysis and hemodialysis patients2024
  4. 4A comparison of the quality of life of the patients undergoing hemodialysis versus peritoneal dialysis and its correlation to the quality of dialysis2016 · 26 citations
  5. 5Health-Related Quality of Life in Home Dialysis Patients Compared to In-Center Hemodialysis Patients: A Systematic Review and Meta-analysis2020 · 72 citations