What question did this study set out to answer?

To update and expand the BRENDA enzyme database with new functional data, standardized vocabularies, and advanced structural search interfaces.

December 17, 2003Nucleic Acids ResearchOpen Access

BRENDA, the enzyme database: updates and major new developments

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To update and expand the BRENDA enzyme database with new functional data, standardized vocabularies, and advanced structural search interfaces.
Curated and extracted biochemical, molecular, and functional parameter data from approximately 46,000 primary literature citations linked to PubMed.
Categorized data across roughly 4,200 EC numbers covering at least 83,000 distinct enzymes from 9,800 organisms.
Implemented a new EC-tree browser, taxonomy browser, ligand chemical substructure search engine, and structured ontologies.
Accelerated database updates, resulting in more than 50% of all data being updated during 2002 and the first half of 2003.
Expanded access to comprehensive biochemical characteristics, including reaction specificity, stability, engineered variants, and disease associations.

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Implication

Database update reports comprehensive expansion of enzyme and metabolic functional records, highlighting improved taxonomic browsing and chemical substructure searches for molecular research.

Cite This Study

Ida Schomburg (2003) studied this question.

synapsesocial.com/papers/6a0193b38d267ec217d8b174 https://doi.org/10.1093/nar/gkh081

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Implication

Database update reports comprehensive expansion of enzyme and metabolic functional records, highlighting improved taxonomic browsing and chemical substructure searches for molecular research.

BRENDA, the enzyme database: updates and major new developments

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Discussion

Implication

Cite This Study

BRENDA, the enzyme database: updates and major new developments

Key Points

Discussion

Implication

Cite This Study

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