Grifolin, grifolic acid, grifolic acid methyl ester and a new compound grifolinol were isolated from methanolic extract of the inedible mushroom Albatrellus dispansus (Scutigeraceae).Their structures were established by a combination of 2D NMR, MS spectrum and chemical reaction.In addition, (+)-and (-)-daurichromenic acids were obtained by cyclization of grifolic acid.The inhibitory activity of TNF-α, anti HIV and antimicrobial activity of grifolic acid derivatives were examined.
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Asakawa et al. (2005) studied this question.
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