Why the study?
Desensitizing catechin corrected diastolic dysfunction in animal models of restrictive cardiomyopathy, but its effects on cardiac function in pediatric cardiomyopathy patients were unknown.
Does green tea extract catechin improve cardiac function in pediatric cardiomyopathy patients with diastolic dysfunction?
Population
12 pediatric cardiomyopathy patients with diastolic dysfunction
Comparison
Catechin administration vs before treatment
Design
Single-arm pre-post study
Follow-up
12 months
Authors
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May suggest diastolic benefit with catechin in pediatric cardiomyopathy; hypothesis-generating case report data requiring controlled trials.
Does green tea extract catechin improve cardiac function in pediatric cardiomyopathy patients with diastolic dysfunction?
Green tea extract catechin administration for 12 months significantly improved echocardiographic parameters of diastolic function in pediatric patients with cardiomyopathy.
Quan et al. (2019) studied this question.
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