Population
Extracts of cells expressing Sendai virus NP, P, and L proteins from plasmids
Comparison
Coexpression of NP and P proteins, and P and L… vs Separate expression and mixing of proteins…
Design
Preclinical
Authors
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Informs antiviral strategies targeting viral protein complexes; leaves open translation beyond animal models.
The formation of NP-P and P-L protein complexes during or soon after synthesis is essential for Sendai virus genome replication and encapsidation.
Horikami et al. (1992) studied this question.
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