Key result
Septal myectomy for hypertrophic obstructive cardiomyopathy has uneven adoption across Europe, with only three centers performing more than 25 procedures per year.
Why the study?
Surgical treatment for hypertrophic cardiomyopathy has seen uneven adoption across Europe, with reliance on alcohol septal ablation and cardiac myosin inhibitors contributing to a decline in surgical expertise.
There are wide disparities in access to septal myectomy across Europe, highlighting an urgent need for structured training and procedural standardization.
Europe has played a foundational role in understanding hypertrophic cardiomyopathy (HCM), yet surgical treatment-particularly septal myectomy-has seen uneven adoption across the continent. Widespread reliance on alcohol septal ablation (ASA) and the more recent introduction of cardiac myosin inhibitors (CMIs) have contributed to a decline in surgical expertise. This perspective reviews the historical evolution of HCM surgery in Europe and the impact of contemporary figures and centers. Drawing on direct correspondence with active European surgeons and institutional data, the manuscript outlines the status of myectomy programs, revealing wide disparities in access, volume, and national coordination. With the data attained here, only three European centers perform more than 25 septal myectomies per year. It also evaluates the clinical and economic implications of surgical versus pharmacological approaches. Emphasis is placed on the urgent need for structured training, procedural standardization, and broader recognition of myectomy as a definitive and cost-effective treatment for obstructive HCM.
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Quintana et al. (2026) conducted a review in Hypertrophic obstructive cardiomyopathy. Septal myectomy vs. Alcohol septal ablation and cardiac myosin inhibitors was evaluated. Septal myectomy for hypertrophic obstructive cardiomyopathy has uneven adoption across Europe, with only three centers performing more than 25 procedures per year.
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