Key result
Simultaneous septal myectomy and anterior mitral leaflet retention plasty significantly decreased the mean left ventricular outflow tract pressure gradient from 98.98 mmHg to 12.3 mmHg and eliminated systolic anterior motion.
Why the study?
Does simultaneous septal myectomy and anterior mitral leaflet retention plasty improve long-term hemodynamic and clinical outcomes in patients with HOCM?
Population
57 patients with hypertrophic obstructive cardiomyopathy and moderate-severe mitral regurgitation, mean age…
Design
Cohort
Follow-up
mean 17.5±1.3 years (median 12, range 1-23.2 years)
Authors
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May inform HOCM surgical planning from extended single-center experience; leaves open comparative efficacy without randomized data.
Cohort (n=57)
No
Does simultaneous septal myectomy and anterior mitral leaflet retention plasty improve long-term hemodynamic and clinical outcomes in patients with HOCM?
Absolute Event Rate: 12.3% vs 98.98%
p-value: p=<0.001
Simultaneous septal myectomy and anterior mitral leaflet retention plasty provides excellent long-term relief of LVOT obstruction and systolic anterior motion in HOCM patients.
Walter et al. (2017) conducted a cohort in Hypertrophic obstructive cardiomyopathy (HOCM) (n=57). Simultaneous septal myectomy and anterior mitral leaflet retention plasty (ALRP) vs. Preoperative baseline was evaluated on Mean left ventricular outflow tract (LVOT) pressure gradient (p=<0.001). Simultaneous septal myectomy and anterior mitral leaflet retention plasty significantly decreased the mean left ventricular outflow tract pressure gradient from 98.98 mmHg to 12.3 mmHg and eliminated systolic anterior motion.
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