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February 28, 2026Herz

T-TEER—interventional repair of tricuspid regurgitation

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Why the study?

Severe tricuspid regurgitation carries an increased risk of morbidity, hospitalization, and mortality, leaving patients at high surgical risk with limited therapeutic options.

Does T-TEER improve outcomes in patients with severe, symptomatic tricuspid regurgitation at high surgical risk?

Population

Patients with severe, symptomatic TR at high surgical risk

Comparison

T-TEER

Design

Review

Key result

Transcatheter tricuspid edge-to-edge repair (T-TEER) reduces tricuspid regurgitation to moderate or less in approximately 81-88% of patients, improving functional status and quality of life.

Authors

DBDominik BerlinerSSSven SchallhornJBJohann Bauersachs

Discussion

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Member takes

Overview

May support T-TEER consideration in high-risk severe TR; leaves open confirmation by randomized trials.

Key Points

  • To evaluate the effectiveness of transcatheter tricuspid edge-to-edge repair in patients with severe tricuspid regurgitation.
  • Minimally invasive intervention using T-TEER
  • High-risk patients with symptomatic severe TR
  • Assessment of TR reduction and functional status
  • 81-88% of patients experienced a reduction of TR to moderate or less
  • Improvements in functional status and quality of life observed
  • Reductions in heart failure-related hospitalizations noted

Structured PICO

Does T-TEER improve outcomes in patients with severe, symptomatic tricuspid regurgitation at high surgical risk?

P
Population
Patients with severe, symptomatic tricuspid regurgitation (TR) at high surgical risk
I
Intervention
Transcatheter tricuspid edge-to-edge repair (T-TEER)
O
Outcome
Reduction of TR to moderate or less

T-TEER represents a safe and effective minimally invasive treatment option for patients with severe, symptomatic tricuspid regurgitation at high surgical risk.

Cite This Study

Berliner et al. (2026) conducted a review in Severe tricuspid regurgitation. Transcatheter tricuspid edge-to-edge repair (T-TEER) was evaluated on Reduction of tricuspid regurgitation to moderate or less. Transcatheter tricuspid edge-to-edge repair (T-TEER) reduces tricuspid regurgitation to moderate or less in approximately 81-88% of patients, improving functional status and quality of life.

synapsesocial.com/papers/6a025a2d9cddff76334129d8https://doi.org/10.1007/s00059-026-05373-x
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