Key result
PVI with pulsed field ablation can trigger delayed coronary vasospasm even without adjacent ablation.
Why the study?
Delayed ischemic events following pulmonary vein isolation-only pulsed field ablation have been rarely described despite known immediate coronary vasospasm risks.
Case Report
Highlights a rare safety signal of delayed coronary vasospasm following PVI-only pulsed field ablation.
Pulsed field ablation (PFA) has emerged as a novel ablation modality that preferentially targets myocardial tissue through irreversible electroporation, offering a favorable safety profile compared with traditional thermal ablation. Although coronary artery vasospasm has been reported during or immediately after PFA—most commonly with cavotricuspid isthmus (CTI) or posterior mitral isthmus ablation—delayed ischemic events following pulmonary vein isolation (PVI)-only PFA have been rarely described.
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Terashima et al. (2026) reported a case report. Pulsed field ablation (PFA) was evaluated on Delayed coronary vasospasm. Delayed coronary vasospasm can occur after pulsed field ablation for pulmonary vein isolation despite avoidance of coronary-adjacent ablation sites.
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