Key result
18F-FDG PET/CT successfully detected a rare non-contiguous tumour thromboembolism in the inferior vena cava of a patient with high-grade osteogenic sarcoma.
Why the study?
Vascular involvement in osteosarcoma is uncommon, and non-contiguous intravascular tumour thromboembolism distant from the primary site is rare and may be underrecognised on conventional imaging.
Case Report (n=1)
Whole-body 18F-FDG PET/CT can add value in detecting unusual metastatic patterns and vascular involvement, such as non-contiguous tumour embolism, in osteosarcoma.
A 42-year-old male presented with a rapidly enlarging, painful swelling in the left distal thigh.Imaging and biopsy confirmed a high-grade osteogenic sarcoma.Baseline metastatic evaluation with 99mTc-Technetium -99m Methylene Diphosphonate (99mTc-MDP) bone scan was negative, while Computed Tomography (CT) thorax revealed two pulmonary nodules suspicious for metastases.
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Mhatre et al. (2026) conducted a case report in Osteogenic sarcoma (n=1). 18F-FDG PET/CT was evaluated. 18F-FDG PET/CT successfully detected a rare non-contiguous tumour thromboembolism in the inferior vena cava of a patient with high-grade osteogenic sarcoma.
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