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June 21, 2005European Heart JournalOpen Access

Heart failure on admission and the risk of stroke following acute myocardial infarction: the VALIANT registry

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Why the study?

Does heart failure on admission increase the risk of in-hospital stroke in patients with acute myocardial infarction?

Population

5,573 consecutive patients with acute myocardial infarction enrolled at 84 international sites from 1999 to…

Comparison

Heart failure on admission (exposure) vs No heart failure on admission

Design

Cohort

Follow-up

in-hospital

Authors

KSKarolina SzummerSSScott D. SolomonEVEric J. Velazquez

Discussion

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Overview

May heighten in-hospital stroke vigilance in AMI with admission heart failure; hypothesis-generating and should not yet change practice.

Structured PICO

Does heart failure on admission increase the risk of in-hospital stroke in patients with acute myocardial infarction?

P
Population
5,573 consecutive patients with acute myocardial infarction enrolled at 84 international sites from 1999 to 2001
I
Intervention
Heart failure on admission (exposure)
C
Comparator
No heart failure on admission
O
Outcome
In-hospital strokehard clinical

The presence of heart failure on admission for an acute myocardial infarction significantly increases the risk of in-hospital stroke, which is associated with a dismal prognosis.

Cite This Study

Szummer et al. (2005) studied this question.

synapsesocial.com/papers/6a026ffa19750436f6cb58fchttps://doi.org/10.1093/eurheartj/ehi352
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Ventricular Dysfunction and the Risk of Stroke after Myocardial Infarction1997 · 604 citations
  2. 2Prognostic Importance of Physical Examination for Heart Failure in Non–ST-Elevation Acute Coronary Syndromes2003 · 259 citations
  3. 3The Risk of Stroke in Patients with Acute Myocardial Infarction after Thrombolytic and Antithrombotic Treatment1992 · 283 citations
  4. 4Platelet Glycoprotein IIb/IIIa Inhibition with Coronary Stenting for Acute Myocardial Infarction2001 · 1,192 citations
  5. 5Stroke After Thrombolysis1995 · 322 citations