Narrative review demonstrates the major contribution of postprandial glycemia to overall glycemic control in type 2 diabetes, highlighting the physiological role of gastric emptying.
The importance of achieving tightglycemic control, usually assessedby glycated hemoglobin (HbA1c), for both the prevention and delay in the progression of diabetes-relatedmicrovascu-lar complications, is established, and the American Diabetes Association/European Association for the Study of Diabetes joint committee has recommended an HbA1c,7 % as the goal in patients with type 2 diabetes (1). The relative contributions of pre- and postprandial glycemia to HbA1c have been clarified during the last decade following the seminal report by Monnier et al. (2) indicating that in type 2 diabetes, postprandial glycemic excursions ac-count for about 70 % of variability when HbA1c is,7.3%, while the contribution
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Marathe et al. (2013) studied this question.
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