Why the study?
Does increased dispersion of repolarization induced by hypothermia and regional warm blood perfusion facilitate the induction of ventricular arrhythmias in open-chest dogs?
Does increased dispersion of repolarization induced by hypothermia and regional warm blood perfusion facilitate the induction of ventricular arrhythmias in open-chest dogs?
Increased dispersion of repolarization to a critical magnitude is required for the induction of ventricular arrhythmias by a premature stimulus in a canine model.
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Supports dispersion of repolarization as arrhythmogenic substrate in canine models; leaves open clinical translation to human ventricular arrhythmias.
Kuo et al. (1985) studied this question.