Why the study?
When transesophageal echocardiography is contraindicated for diagnosing infective endocarditis, other alternative imaging modalities have significant limitations, positioning intracardiac echocardiography as a potential alternative.
Can intracardiac echocardiography be used to diagnose infective endocarditis in patients with contraindications to transesophageal echocardiography?
Can intracardiac echocardiography be used to diagnose infective endocarditis in patients with contraindications to transesophageal echocardiography?
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Intracardiac echocardiography may serve as a viable alternative for diagnosing infective endocarditis when standard imaging modalities are contraindicated or unavailable.
Infective endocarditis (IE) can lead to significant morbidity and mortality without appropriate treatment. Modified Duke Criteria are accepted by many professional societies to establish the diagnosis of IE, and cardiac imaging is one of the major diagnostic criteria. Transesophageal echocardiography is an algorithmic escalation to diagnose IE when transthoracic echo does not appreciate a positive finding. In patients with contraindications to transesophageal echocardiography, cardiac magnetic resonance imaging, cardiac computed tomography (CT), cardiac CT angiography, and fluorodeoxyglucose positron emission tomography with CT or CT angiography may be alternative diagnostic tools. However, these imaging modalities have their own limitations such as local unavailability, the presence of non-magnetic resonance imaging compatible implants, or impaired renal function. Intracardiac echocardiography could be a considerable alternative under those circumstances.
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Yang et al. (2019) studied this question.
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