Time Elapsed After Ischemic Stroke and Risk of Adverse Cardiovascular Events and Mortality Following Elective Noncardiac Surgery
Why the study?
Does the time elapsed between an ischemic stroke and elective noncardiac surgery affect the risk of 30-day MACE and mortality compared to patients without prior stroke?
Population
481,183 elective noncardiac surgeries in patients aged 20 years or older, including 7,137 with prior…
Comparison
Elective noncardiac surgery performed at… vs Elective noncardiac surgery in patients without…
Design
Cohort
Follow-up
30 days
Authors
Discussion
Loading...
Member takes
Implication
May support delaying elective surgery >9 months post-stroke if feasible; leaves open need for randomized confirmation of optimal timing.
Structured PICO
Does the time elapsed between an ischemic stroke and elective noncardiac surgery affect the risk of 30-day MACE and mortality compared to patients without prior stroke?
P
Population
481,183 elective noncardiac surgeries in patients aged 20 years or older, including 7,137 with prior ischemic stroke and 474,046 without prior stroke.
I
Intervention
Elective noncardiac surgery performed at specific time intervals (<3 months, 3 to <6 months, 6 to <12 months, ≥12 months) after an ischemic stroke.
C
Comparator
Elective noncardiac surgery in patients without a history of stroke.
O
Outcome
Major adverse cardiovascular events (MACE; including ischemic stroke, acute myocardial infarction, and cardiovascular mortality) up to 30 days after surgery.composite
Elective noncardiac surgery performed within 9 months of an ischemic stroke is associated with a significantly elevated risk of perioperative MACE and mortality, suggesting procedures should be delayed beyond this window if possible.
Cite This Study
Jørgensen et al. (2014) studied this question.