Why the study?
Significant differences exist in CAD pathophysiology between women and men, alongside persistent sex disparities in acute coronary syndrome care from diagnostic delays and treatment inconsistencies.
This review summarizes key recommendations from the 2021 AHA/ACC Chest Pain Guideline specifically tailored to the evaluation and management of chest pain in women.
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May aid sex-specific chest pain evaluation in women per 2021 guidelines; leaves open prospective validation for INOCA strategies.
Chest pain is a common concern of women evaluated in both the inpatient and outpatient setting. There are significant differences in pathophysiology when comparing coronary artery disease (CAD) in women and men, including a higher prevalence of nonobstructive CAD. Furthermore, significant sex disparities exist in the care of women with acute coronary syndromes that stem from factors such as delays in diagnosis and inconsistencies in treatment. The 2021 AHA/ACC/Multisociety Guideline for the Evaluation and Diagnosis of Chest pain is an important document comprised of recommendations for the assessment of acute and stable chest pain. In this review, we discuss key points from the guideline in the context of evaluating chest pain in women. We discuss the similarities and differences of chest pain presentation between the sexes, evaluation of chest pain in patients with known nonobstructive CAD and ischemia with no obstructive coronary arteries, and considerations for cardiac imaging during pregnancy.
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Kaur et al. (2023) studied this question.
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