Why the study?
Does adenosine deaminase (ADA) activity differentiate the aetiology of pleural effusions?
Population
90 patients with pleural effusions of various aetiology
Comparison
Measurement of adenosine deaminase activity in… vs Comparison among different aetiologies
Design
Cross-sectional
Authors
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ADA elevation may aid differentiation of tuberculous and rheumatoid effusions; leaves open prospective validation of diagnostic thresholds.
Does adenosine deaminase (ADA) activity differentiate the aetiology of pleural effusions?
ADA activity in pleural fluid is significantly elevated in tuberculous, empyema, and rheumatoid effusions, suggesting local synthesis and potential diagnostic utility.
Pettersson et al. (1984) studied this question.
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