Why the study?
Does long-term use of antihypertensive medications increase the risk of invasive ductal and invasive lobular breast cancers in postmenopausal women aged 55 to 74 years?
Population
2,763 postmenopausal women aged 55 to 74 years in the Seattle-Puget Sound metropolitan area, including 880…
Comparison
Antihypertensive medications, assessed by… vs Non-use or shorter duration of use of…
Design
Case-control
Authors
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No change to prescribing warranted; hypothesis-generating association requires prospective confirmation.
Does long-term use of antihypertensive medications increase the risk of invasive ductal and invasive lobular breast cancers in postmenopausal women aged 55 to 74 years?
Long-term use (10 or more years) of calcium-channel blockers is associated with a significantly increased risk of invasive ductal and lobular breast cancers in postmenopausal women.
Li et al. (2013) studied this question.
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