What question did this study set out to answer?

To evaluate the long-term impact of postoperative atrial fibrillation on future arrhythmia recurrence and overall mortality following aortocoronary bypass surgery.

February 6, 2010European Journal of Cardio-Thoracic Surgery

Postoperative atrial fibrillation in patients undergoing aortocoronary bypass surgery carries an eightfold risk of future atrial fibrillation and a doubled cardiovascular mortality

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Why the study?

Does postoperative atrial fibrillation increase the risk of future atrial fibrillation and mortality in patients undergoing aortocoronary bypass surgery?

Population

571 patients with no history of atrial fibrillation who underwent primary aortocoronary bypass surgery from…

Comparison

Postoperative atrial fibrillation (AF) vs No postoperative atrial fibrillation

Design

Cohort

Follow-up

median 6 years

Authors

AAAnders AhlssonCardiac Surgery EFEspen FengsrudÖrebro University LBLennart BodinKarolinska Institutet

Discussion

Member takes

Implication

Postop AF after CABG may warrant closer long-term surveillance; leaves open causal effects and intervention benefits in observational data.

Key Points

To evaluate the long-term impact of postoperative atrial fibrillation on future arrhythmia recurrence and overall mortality following aortocoronary bypass surgery.
Followed a cohort of 571 patients without prior atrial fibrillation undergoing primary aortocoronary bypass surgery between 1999 and 2000.
Tracked outcomes over a median follow-up of 6 years via follow-up questionnaires (91.6% of survivors), electrocardiograms (88.6% of patients), hospital records for arrhythmia or stroke, and death records.
At follow-up, late atrial fibrillation occurred in 25.4% of patients with postoperative AF compared to 3.6% without (p < 0.001), representing an adjusted risk ratio of 8.31 (95% CI 4.20–16.43).
Overall mortality was significantly higher in the postoperative AF group compared to the non-AF group (29.7% vs 14.8%, p < 0.001; adjusted HR 1.57, 95% CI 1.05–2.34).
Deaths resulting from cerebral ischaemia (4.2% vs 0.2%, p < 0.001) and myocardial infarction (6.7% vs 3.0%, p = 0.041) were significantly increased among patients who experienced postoperative AF.

Structured PICO

Does postoperative atrial fibrillation increase the risk of future atrial fibrillation and mortality in patients undergoing aortocoronary bypass surgery?

Population

571 patients with no history of atrial fibrillation who underwent primary aortocoronary bypass surgery from 1999 to 2000

Intervention

Postoperative atrial fibrillation (AF)

Comparator

No postoperative atrial fibrillation

Outcome

Development of late atrial fibrillation and long-term mortality at median 6 years follow-uphard clinical

Postoperative AF after CABG is not a benign, transient event but is associated with a significantly increased risk of future AF and long-term cardiovascular mortality.

Cite This Study

Ahlsson et al. (2010) studied this question.

synapsesocial.com/papers/6a03bf73d2c35e4200e96a2c https://doi.org/10.1016/j.ejcts.2009.12.033

Topics

Atrial fibrillation Persistent AF management Anticoagulation in AF AF ablation outcomes

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Implication

Postop AF after CABG may warrant closer long-term surveillance; leaves open causal effects and intervention benefits in observational data.

Postoperative atrial fibrillation in patients undergoing aortocoronary bypass surgery carries an eightfold risk of future atrial fibrillation and a doubled cardiovascular mortality

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Postoperative atrial fibrillation in patients undergoing aortocoronary bypass surgery carries an eightfold risk of future atrial fibrillation and a doubled cardiovascular mortality

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

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