Why the study?
The extent of platelet involvement in venous thromboembolism is not fully understood, and the role of immature platelets in VTE had not been previously investigated.
How does venous thromboembolism affect immature platelet fraction, absolute platelet count, and platelet aggregation over time compared to healthy controls?
Population
Patients with VTE and 50 age- and sex-similar healthy volunteer controls
Comparison
Patients with VTE vs healthy volunteer controls
Follow-up
90-110 days
Authors
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VTE-associated platelet changes may reflect consumption; hypothesis-generating for immature platelet indices in monitoring and future trials.
How does venous thromboembolism affect immature platelet fraction, absolute platelet count, and platelet aggregation over time compared to healthy controls?
VTE is associated with measurable changes in platelet parameters over time, suggesting relevant platelet consumption during venous thromboembolism.
Wustrow et al. (2020) studied this question.
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