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September 1, 1993The Journal of Experimental MedicineOpen Access

Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells.

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Authors

ADAnnalisa D’AndreaKaneka (United States)MAMiguel Aste-AmézagaUnited States Military AcademyNVNicholas M. ValianteInnovate UK

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Cite This Study

D’Andrea et al. (1993) studied this question.

synapsesocial.com/papers/6a03e7d89439d975f42b2f40https://doi.org/10.1084/jem.178.3.1041
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells.1992 · 1,162 citations
  2. 2IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells1991 · 1,872 citations
  3. 3Regulation of gamma interferon production by natural killer cells in scid mice: roles of tumor necrosis factor and bacterial stimuli1991 · 211 citations
  4. 4Regulation of human lymphocyte proliferation by a heterodimeric cytokine, IL-12 (cytotoxic lymphocyte maturation factor)1991 · 461 citations
  5. 5IL-10 inhibits cytokine production by activated macrophages1991 · 2,921 citations